Funding for this trial has been provided in full or in part by Cystic Fibrosis Foundation Therapeutics, Inc.
High Flow Nasal Insufflation/HFNI
Number of Participants Being Recruited:
Single / Multi-Center:
STUDY BACKGROUND INFORMATION:
People with cystic fibrosis (CF) often lose weight because they have problems with breathing and lung infections. It becomes harder to breathe and gain weight as lung disease gets worse. Children with CF breathe a lot harder during sleep. This could be one reason why they have trouble gaining weight. A new treatment has been developed that delivers warm and humid air. This study will look to see if this treatment will help people with CF breathe easier when they sleep and as a result help people with CF gain weight. This study will include overnight sleep studies.
7 Years - 80 Years
P. aeruginosa status:
B. cepacia status:
Other Primary Eligibility Requirements:
Exclusion criteria include: 1) severe ventilatory impairment requiring treatment with BiPAP or mechanical ventilation; 2) daytime hypoxemia (SaO2<90% at rest); 3) sinus or nasal surgery within 4 weeks of enrollment; and 4) pregnancy.
Note: Detailed eligibility criteria information may be available on clinicaltrials.gov. If a specific
trial listing for this trial is available, a link to the specific clinicaltrials.gov listing will be present in the "More Information" section below.
The sites listed below are currently recruiting subjects. Please note that this list generally lists either the pediatric or adult program but not both even though both programs may be recruiting subjects. Also, this list does not include sites that may be participating in the study but are not yet open for recruitment. If you are interested in this study please contact your center for more information.