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Study Name: Effect of Proton Pump Inhibitors on CF Exacerbations
Study Type: Interventional
Intervention Category: Other
Study Sponsor: DiMango, Emily

Funding for this trial has been provided in full or in part by Cystic Fibrosis Foundation Therapeutics, Inc.
Study Phase: 2
Recruitment Status: Trial Completed
Study Drug(s): Esomeprazole Magnesium
Number of Participants Being Recruited: 50
Single / Multi-Center: Multi-Center
Gastroesophageal reflux disease (GERD) is a common problem in cystic fibrosis. It may lead to worsening lung function and more respiratory infections for a person with CF. This study will look at treating GERD with a medication, esomeprazole. This medication stops stomach acid from being made. The study will see if there is less respiratory infections and improved lung function in patients with CF when taking esomeprazole.
Age: >= 18 Years
FEV1: Not Applicable
P. aeruginosa status: Not applicable
B. cepacia status: Not applicable
Other Primary Eligibility Requirements:

Note: Detailed eligibility criteria information may be available on If a specific trial listing for this trial is available, a link to the specific listing will be present in the "More Information" section below.
Sponsor Contact Information: DiMango, Emily
(212) 305-0290
Trial Specific Link on Not Available
Clinical Research Terms Glossary: Click here
The sites listed below are currently recruiting subjects. Please note that this list generally lists either the pediatric or adult program but not both even though both programs may be recruiting subjects. Also, this list does not include sites that may be participating in the study but are not yet open for recruitment. If you are interested in this study please contact your center for more information.
  • Beth Israel Medical Center (Adult), New York, NY, 10003
    Contact Information:
        Grece, Carroll Anne
        Phone: (212) 420-4196
  • Beth Israel Medical Center (Adult), New York, NY, 10003
    Contact Information:
        DiBenedetto, Donna
        Phone: (212) 420-4100
  • Columbia University, Adult Cystic Fibrosis Program (Adult), New York City, NY, 10032
    Contact Information:
        DiMango, Emily
        Phone: (212) 305-0290
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