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Study Name: The Effect of Azithromycin on TGF-b1
Study Type: Interventional
Intervention Category: Anti-Infective
Study Sponsor: Harris, William

Funding for this trial has been provided in full or in part by Cystic Fibrosis Foundation Therapeutics, Inc.
Study Phase: Other
Recruitment Status: Trial Completed
Study Drug(s): Azithromycin
Number of Participants Being Recruited: 22
Single / Multi-Center: Single Center
Recent genetic studies have shown that CF patients with a variation in the gene for TGF-b1, a key regulator of immune function and tissue repair, are twice as likely to have severe lung disease. This study will examine if TGF-b1 is reduced when taking Azithromycin
Age: >= 8 Years
FEV1: >= 40 Percent Predicted
P. aeruginosa status: Not applicable
B. cepacia status: Not applicable
Other Primary Eligibility Requirements:

Note: Detailed eligibility criteria information may be available on If a specific trial listing for this trial is available, a link to the specific listing will be present in the "More Information" section below.
Sponsor Contact Information:
Trial Specific Link on Not Available
Clinical Research Terms Glossary: Click here
The sites listed below are currently recruiting subjects. Please note that this list generally lists either the pediatric or adult program but not both even though both programs may be recruiting subjects. Also, this list does not include sites that may be participating in the study but are not yet open for recruitment. If you are interested in this study please contact your center for more information.
  • University of North Carolina at Chapel Hill (Pediatric), Chapel Hill, NC, 27599
    Contact Information:
        Barlow, Carol
        Phone: (919) 966-9146
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