|
|
| Study Name: |
PharmaNAC Phase 2b: N-Acetylcysteine Effects in CF |
| Study Type: |
Interventional |
| Intervention Category: |
Anti-Inflammatory |
| Study Sponsor: |
Conrad, Carol
Funding for this trial has been provided in full or in part by Cystic Fibrosis Foundation Therapeutics, Inc. |
| Study Phase: |
2 |
| Recruitment Status: |
Trial Completed |
| Study Drug(s): |
N-Acetylcystiene (Oral) |
| Number of Participants Being Recruited: |
70 |
| Single / Multi-Center: |
Multi-Center |
| STUDY BACKGROUND INFORMATION: |
| This study will look at the effects of an investigational product called N-acetylcysteine (NAC) on the basic processes that cause inflammation in CF lung disease. We hope to learn more about the causes of lung disease in cystic fibrosis by studying the characteristics of the inflammation in the lungs of patients who have CF. |
| Age: |
>= 7 Years
|
| FEV1: |
40 - 85 Percent Predicted
|
| P. aeruginosa status: |
Not applicable |
| B. cepacia status: |
Not applicable |
Other Primary Eligibility Requirements:
|
| Note: Detailed eligibility criteria information may be available on clinicaltrials.gov. If a specific
trial listing for this trial is available, a link to the specific clinicaltrials.gov listing will be present in the "More Information" section below. |
| Sponsor Contact Information: |
Hocevar-Trnka, Jasna
(206) 884-7527
jasna.hocevar-trnka@seattlechildrens.org
|
| PARTICIPATING SITES: |
| The sites listed below are currently recruiting subjects. Please note that this list generally lists either the pediatric or adult program but not both even though both programs may be recruiting subjects. Also, this list does not include sites that may be participating in the study but are not yet open for recruitment. If you are interested in this study please contact your center for more information. |
| AL |
-
The Children's Hospital/University of Alabama at Birmingham (Pediatric), Birmingham, AL, 35233
Contact Information:
Hathorne, Heather
Phone: (205) 638-9568
Email: hhathorne@peds.uab.edu
|
| CA |
-
Stanford University Medical Center (Pediatric), Palo Alto, CA, 94304
Contact Information:
Dunn, Colleen
Phone: (650) 736-0388
Email: cedunn@stanford.edu
|
| CO |
-
National Jewish Health (Adult), Denver, CO, 80206
Contact Information:
Jones, Marion
Phone: (303) 398-1265
Email: jonesm@njhealth.org
|
| CT |
-
Yale University School of Medicine (Pediatric), New Haven, CT, 06520
Contact Information:
Young, Jane
Phone: (203) 785-5852
Email: jane.young@yale.edu
|
| FL |
-
University of Florida (Pediatric), Gainesville, FL, 32610
Contact Information:
Baker, Dawn
Phone: (352) 273-5417
Email: bakerdj@peds.ufl.edu
|
| NC |
-
Duke University Medical Center (Pediatric), Durham, NC, 27710
Contact Information:
Auten, Kathy
Phone: (919) 684-2281
Email: kathy.auten@duke.edu
|
| NY |
-
Columbia University, Adult Cystic Fibrosis Program (Adult), New York City, NY, 10032
Contact Information:
Robinson, Victoria
Phone: (212) 305-0686
Email: vgr2103@columbia.edu
|
| PA |
-
Hershey Medical Center Pennsylvania State University (Pediatric), Hershey, PA, 17033
Contact Information:
Kitch, Diane
Phone: (717) 531-5646
Email: dkitch@psu.edu
-
Children's Hospital of Philadelphia University of Pennsylvania (Pediatric), Philadelphia, PA, 19104
Contact Information:
Kubrak, Christina
Phone: (267) 426-5135
Email: kubrak@email.chop.edu
-
Children's Hospital of Pittsburgh of UPMC (Pediatric), Pittsburgh, PA, 15213
Contact Information:
Hartigan, Elizabeth
Phone: (412) 692-7060
Email: elizabeth.hartigan@chp.edu
|
| UT |
-
Intermountain Cystic Fibrosis Center (Pediatric), Salt Lake City, UT, 84132
Contact Information:
Vroom, Jane
Phone: (801) 587-7458
Email: jane.vroom@hsc.utah.edu
|
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