A biorepository is a place, similar to a library or bank, where biological samples are stored for use in research. Biological samples are collected from patients who provide consent to physicians and researchers to use their blood or bodily fluids for scientific and medical research.
Biorepository samples come in many different forms: blood, urine, stool, tissue and other material. These samples are stored under appropriate conditions that ensure they are preserved for future analysis.
Since 2006, the Cystic Fibrosis Foundation has collected and stored samples from a variety of clinical trials. The CF Foundation has developed a database that combines information from these samples with data from CF clinical trials and the CF Foundation Patient Registry to create a unique and specific sample profile.
It is the Foundation’s goal to get these samples into the hands of qualified researchers to help develop promising new studies that will support CF research, drug development and drug discovery.
Clinical Sample Acquisition Process
The Cystic Fibrosis Foundation is accepting applications from qualified investigators who wish to gain access to biospecimens and clinical trial data for use in translational scientific research. Applications undergo a comprehensive review for scientific merit and impact.
All applicants must first submit a Letter of Intent (LOI) so the CF Foundation can assess the feasibility of samples being requested and evaluate the impact the request will have on the biobank. Accepted LOIs will be asked to submit a full application that will undergo a committee review and scoring to examine the scope and goals of the research project.
The CF Foundation provides guidance to investigators about areas of CF research that it considers to be high priorities for scientific evaluation. The following are key focus areas:
Forms and Guidance Documents for Qualified Investigators