Drug Development Pipeline
PTI-801 (alone and in combination)
Status
Phase TwoTherapeutic Approach
Restore CFTR Function
PTI-801 is a new CFTR corrector. Correctors are drugs designed to fix and restore the function of the defective CFTR protein. The corrected CFTR then moves to the cell surface, where it functions as a chloride channel and helps maintain the right balance of fluid in the airways.
PTI-801 is currently being studied both alone as well as in combination with two other CFTR modulators, PTI-428 and PTI-808.
Status
A phase 1 & 2 study to test the safety and tolerability of PTI-801 is underway.
Sponsor
This program is sponsored by Proteostasis Therapeutics. It is being conducted through the Therapeutics Development Network.
Recent PTI-801 (alone and in combination) Studies
Sign up for clinical trial alerts
Get email updates about clinical trials that matter to you.
Explore clinical trials
Be a part of the movement transforming the future of cystic fibrosis treatment.
Learn More