Drug Development Pipeline
Restore CFTR Function
Dirocaftor is a type of CFTR modulator called a potentiator. Potentiators help facilitate the opening of the chloride channel on the cell surface to allow chloride and sodium (salt) to move in and out of the cell.
Phase 2 studies have been conducted to test the safety and effectiveness of dirocaftor in combination with two other CFTR modulators, posenacaftor (PTI-801) and nesolicaftor (PTI-428).
This program is sponsored by Proteostasis Therapeutics. It is being conducted through the Therapeutics Development Network.
Recent Dirocaftor (PTI-808) Studies
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