Clinical Trial Finder
About Therapeutic Approaches
A therapeutic approach refers to the type of treatment or therapy being studied. A therapy could range from a drug or vitamin to a device or activity (e.g., exercise). Find more information below about different therapeutic approaches.
Restore CFTR Function
The symptoms of cystic fibrosis are caused by a defective protein, known as the cystic fibrosis transmembrane conductance regulator (CFTR). Researchers are investigating whether these potential drugs or technologies can restore function to the CFTR protein or correct its production process so that a normal protein is produced.
Mucociliary ClearanceThese clinical trials are designed to thin or alter the thick, sticky mucus in the lungs of people with cystic fibrosis so that it can be coughed out more easily.
These clinical trials are focused on potential drugs that can reduce inflammation and prevent or lessen damage to healthy lung tissue.
Researchers are exploring new ways to fight infections caused by bacteria, viruses and fungi.
These potential therapies seek to improve the nutrition of people with cystic fibrosis by breaking down food better or providing nutrients that people with CF have trouble absorbing.
Behavioral studies are designed to identify and understand how factors, such as self-management, mental health and social support, are associated with health outcomes. They also look at how the participant’s health affects behavior and social functioning. The goal of interventions is to find effective counseling and supportive approaches to optimize the overall well-being of people with CF and their families.
This is a type of clinical trial in which researchers observe certain aspects of routine care and track health outcomes. These studies are very important for developing new ideas about CF and how the disease might best be treated.
These studies include any other type of clinical trial to test an intervention or potential treatment.
Clinical trials that test potential drugs and therapies in people with cystic fibrosis are a major part of CF research. They take place at Cystic Fibrosis Foundation-accredited care centers all over the United States and enroll people with CF of all ages.
Nothing is more important than patient safety in developing new treatments for cystic fibrosis. The U.S. government requires that all clinical trials are supervised for safety, and the Cystic Fibrosis Foundation adds additional measures to protect study volunteers.
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