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Clinical Trials | Our Research Approach CF Foundation Funds Expansion of Clinical Trial Program for Potential Nonsense Mutations Therapy

The Cystic Fibrosis Foundation is awarding up to $15.9 million in additional funding to Eloxx Pharmaceuticals Inc. to expand clinical studies of ELX-02, a potential therapy for people with CF who have nonsense mutations.

| 4 min read
About the CF Foundation | Clinical Trials | Our Research Approach Cystic Fibrosis Foundation Awards Up to $3.5M to Arrevus Inc. to Develop Treatment for Pulmonary Exacerbations

The Cystic Fibrosis Foundation awarded up to $3.5 million to Arrevus Inc. to test a potential treatment for pulmonary exacerbations in people with cystic fibrosis in a late phase clinical trial.

| 1 min read
About the CF Foundation | Clinical Trials | Our Research Approach CF Foundation Awards Up to $4.7M to EnBiotix Inc. to Develop Inhaled Antibiotic to Treat Pseudomonas

The Cystic Fibrosis Foundation awarded up to $4.7 million to EnBiotix Inc. to study the potential use of inhaled colistin as an additional option to treat Pseudomonas infections in people with cystic fibrosis who are not responding to current treatments.

| 2 min read
About the CF Foundation | Clinical Trials | Our Research Approach CF Foundation Awards Up to $5 Million to BiomX for Potential Phage Therapy

Study reaffirms the Foundation’s commitment to advance solutions to the growing challenge of antibiotic resistance

| 4 min read
Research | About the CF Foundation | Clinical Trials CF Foundation Awards Up to $2M to Eloxx for Additional Support for Studies into Nonsense Mutations Therapy

Today, the Cystic Fibrosis Foundation announced a new award of up to $2 million to Eloxx Pharmaceuticals Inc. to support the global Phase 2 clinical program of ELX-02, a potential therapy to treat people with cystic fibrosis who have nonsense mutations.

| 4 min read
Clinical Trials First-of-Its-Kind Study Uses Smartphone to Track Cystic Fibrosis in Real Life

Observational study supported by the CF Foundation will monitor real-world experience with Trikafta

| 4 min read
Clinical Trials Anti-Inflammatory Drug for CF Fails to Meet Goal of Late-Stage Clinical Trial

Corbus Pharmaceuticals reported today that the Phase 2b clinical trial of its potential anti-inflammatory drug lenabasum did not meet its primary objective of decreasing pulmonary exacerbations in people with cystic fibrosis.

| 2 min read
Drug Pipeline | Clinical Trials Vertex Announces Positive Study Results for Trikafta in Children Ages 6-11

Today, Vertex Pharmaceuticals Inc. announced positive Phase 3 clinical trial data for Trikafta® (elexacaftor/tezacaftor/ivacaftor) in children 6-11 years old with cystic fibrosis.

| 2 min read
Research | About the CF Foundation | Clinical Trials | Our Research Approach CF Foundation Announces up to $5M Award to Support First-Ever Controlled Clinical Study of Phage Therapy in Cystic Fibrosis

Study reaffirms the Foundation's commitment to advance solutions to the growing challenge of antibiotic resistance and evaluate the use of phage to treat infections for people with CF

| 4 min read
Research | Clinical Trials | Our Research Approach CF Foundation Awards Funding for First-Ever Controlled Clinical Study of Phage Therapy in CF

The Cystic Fibrosis Foundation awarded up to $5 million to Armata Pharmaceuticals for the first-ever controlled clinical study of phage therapy in CF, reaffirming the Foundation's commitment to advance innovative solutions to the growing challenge of antibiotic resistance.

| 3 min read