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Here's what you need to know about the four CFTR (cystic fibrosis transmembrane conductance regulator) modulators.

New data show positive results in individuals with a single F508del mutation as well as people with two copies of F508del and support continued development of triple combination therapies. 

Researchers are exploring treatments that will keep people with cystic fibrosis as healthy as possible until a cure is found. In the first plenary at the NACFC, two CF scientists explain the progress of current research.

For those of us without a medication that targets our cystic fibrosis mutation, it's important to remember that our life with CF is a marathon.

The New England Journal of Medicine, the world's most influential and widely read medical periodical, features a study this week about a Phase 2 clinical trial of VX-770, an oral drug in development that targets the root cause of cystic fibrosis.