IONIS-ENaC-2.5

IONIS-ENaC-2.5_Rx is a compound designed to block the function of the sodium (Na+) channel found in the lungs. These channels move sodium and water away from the airway surface. Blocking these channels may help maintain fluid within the airways to improve mucus clearance.

Status

A phase 1/2a study to test the safety and tolerability of IONIS-ENaC-2.5_Rx in healthy volunteers and in adults with CF is underway.

Sponsor

This program is sponsored by Ionis Pharmaceuticals and partially funded by the Cystic Fibrosis Foundation.