Cystic Fibrosis Foundation Therapeutics, Inc. and Genaera Corporation have agreed to discontinue the Phase 2 clinical evaluation of Lomucin for CF because it was deemed unlikely that continued enrollment of patients into the study would ever result in the drug being proven effective.
The study was terminated based on a recommendation by Genaera to the study's Data Monitoring Committee. The committee identified no
About two-thirds of the drugs that make it past Phase 1 testing continue on to Phase 2 trials. Safety and effectiveness are examined in these trials. In most Phase 2 trials, one group of volunteers may be given the
Currently, there are nearly 30 potential therapies in the CF Foundation's drug development pipeline. It is estimated that only one in five new drugs that enter clinical trials will become an approved therapy for patients. This is why the Foundation must continuously feed the drug development pipeline to better the success for all people with CF.