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Research | CFTR Modulators FDA Approves Expansion of Modulators for People With Certain Rare Mutations

The U.S. Food and Drug Administration (FDA) today expanded its approval of three CFTR modulators to include additional people with CF who have certain rare mutations. The approval enables more than 600 individuals with CF who were not previously eligible for modulators to access drugs that treat the underlying cause of their disease for the first time.

| 3 min read
Research | CFTR Modulators Roche Acquires Potential CF Therapies; Plans to Develop Alternatives to CFTR Modulators

Roche has acquired a set of potentiator compounds from Enterprise Therapeutics and intends to study them for the treatment of CF. The Cystic Fibrosis Foundation previously provided funding to Enterprise to develop these potential medicines.

| 3 min read
Research | About the CF Foundation | Our Research Approach CF Foundation Awards Nearly $15 Million to Spur Infection Research

Thirty-three new projects are being funded as part of the Foundation's $100 million Infection Research Initiative.

| 4 min read
Research | Antibiotics | Our Research Approach CF Foundation Awards Up to $5.6 Million to Develop Novel Antibiotic to Fight Drug-Resistant Bacteria

The Cystic Fibrosis Foundation has awarded up to $5.6 million to Microbion Corporation to develop a novel, inhaled antibiotic to treat drug-resistant bacterial infections in people with cystic fibrosis.

| 2 min read
Research | Clinical Trials | Our Research Approach CF Foundation Awards Funding for First-Ever Controlled Clinical Study of Phage Therapy in CF

The Cystic Fibrosis Foundation awarded up to $5 million to Armata Pharmaceuticals for the first-ever controlled clinical study of phage therapy in CF, reaffirming the Foundation's commitment to advance innovative solutions to the growing challenge of antibiotic resistance.

| 3 min read
Research | Our Research Approach Cystic Fibrosis Foundation Supports Development of Non-Porcine Enzyme Therapy

The Cystic Fibrosis Foundation has entered into an agreement with Synspira Therapeutics Inc. to develop a non-porcine enzyme replacement therapy to offer an alternative to people with cystic fibrosis who cannot digest food properly.

| 2 min read