CF Foundation Invests Up to $2 Million in Nosis Bio for Potential Gene Therapy Delivery Technology

Nosis Bio, an inaugural winner of the Foundation’s Golden Ticket Competition, receives funding to further explore design of novel ligands, which are specialized molecules that could help more precise targeting of relevant cells in the lung. 

July 18, 2023 | 3 min read

BETHESDA, Md. — The Cystic Fibrosis Foundation recently agreed to provide up to $2 million to Nosis Bio to explore an alternative way to safely deliver gene therapies into the appropriate lung cells, a key challenge in cystic fibrosis. This type of therapy has the potential to treat anyone with CF, including those with rare and nonsense mutations.

Nosis Bio uses artificial intelligence (AI) to design and develop novel drug delivery molecules, called Targeted Delivery Vehicles (TDVs). For this research, Nosis intends to develop TDVs that enable the targeting of specific cells in the lung without provoking an unwanted immune response.

In July 2022, Nosis was announced as a winner of the Foundation’s inaugural “Golden Ticket” Competition, an opportunity for early-stage companies working to translate research into a potential therapy. Since then, Nosis was awarded free laboratory space and support at Bakar Labs, the incubator at the University of California Berkley’s Bakar BioEnginuity Hub, and given access to the Foundation’s unparalleled research infrastructure, including the ability to collaborate with the world's foremost experts in CF to advance their work.

The Foundation is committed to attracting new innovative companies into CF by de-risking early-stage science as part of its Path to a Cure initiative, which aims to accelerate treatments and drug development for the underlying cause of the disease, and ultimately deliver a cure for CF.

Companies at any stage of development are encouraged to apply for the Foundation’s industry funding opportunities

About the Cystic Fibrosis Foundation

The Cystic Fibrosis Foundation is the world's leader in the search for a cure for cystic fibrosis. The Foundation funds more CF research than any other organization, and nearly every CF drug available today was made possible because of Foundation support. Based in Bethesda, Md., the Foundation also supports and accredits a national care center network that has been recognized by the National Institutes of Health as a model of care for a chronic disease. The CF Foundation is a donor-supported nonprofit organization. For more information, visit  

Media Contact
Dee Donavanik
Phone: 240-482-2857

Industry Contact
Lindsey Beaman
Phone: 240-200-3780

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