Complications of cystic fibrosis affect everyone with the disease, regardless of their mutation. We are supporting research into CF complications, such as infections, inflammation, excessive mucus, and gastrointestinal issues, to develop better treatments and improve outcomes for people with CF.
People with cystic fibrosis are prone to infections because of the thick, sticky mucus that clogs their airways. The Cystic Fibrosis Foundation is funding research to help fight these infections.
Chronic inflammation in people with cystic fibrosis causes damage to lung tissue that can eventually lead to respiratory failure. Researchers are trying to discover ways to dampen the exaggerated immune response that causes chronic inflammation without affecting the body's natural defenses against infection.
People with cystic fibrosis have thick, sticky mucus that blocks passages in their lungs, making it difficult for them to breathe and predisposing them to infections. New drugs are under development that will help break up and hydrate mucus in the lungs to make it easier to clear.
People with cystic fibrosis can experience complications in the pancreas, liver, and intestines that can lead to malnutrition, constipation, liver disease, and other digestive issues -- including abdominal pain and poor appetite. Learn about research underway to address digestive system issues in CF.