CFF/NIH R01-Unfunded Award

The objective of this award is to support excellent cystic fibrosis-related research projects that have been approved by the National Institutes of Health (or governmental funding agencies in other countries) but cannot be supported by available funds.

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As a result of funding constraints on governmental agencies in the United States and other countries, coupled with the growing interest in cystic fibrosis research, occasions arise in which highly meritorious grant applications are submitted to these governmental agencies but are not funded. The Cystic Fibrosis Foundation does not intend to assume the role of the National Institutes of Health (NIH) or other governmental funding agencies elsewhere, but instead wishes to ensure that the momentum in CF research is not irreversibly slowed.

Support from the Cystic Fibrosis Foundation is intended to provide for the development of preliminary data to make CF-related grant applications highly competitive at the NIH (or in review processes of governmental funding agencies in other countries).

To be considered for this program, applications must have been submitted to:

NIH as an R01 and fall within the upper 40th percentile


Governmental funding agencies in other countries with an NIH R01-equivalent funding program that provides reviewer critiques and a report indicating the application scored in the upper 40th percentile. 

In both cases, the applications must be able to be resubmitted to the funding agency within one year of receiving a CFF/NIH R01-Unfunded Award to be eligible for consideration.

Note: Fellowship applications and other funding mechanisms other than R01 (or equivalent) do not qualify for this program.

The CF Foundation offers funding of up to $125,000 per year for up to two years. (Indirect costs are not allowable.)

Policies and Guidelines

Please review the 2024 Policies and Guidelines for complete submission information.


Applications must be submitted online at by 5 p.m. ET on December 2, 2024.

For More Information

Those who are interested in any funding programs offered by the CF Foundation can get further information, or discuss the potential relevance of their studies or research by contacting the Grants and Contracts Management and Administration (GCMA) Office at

Please Direct Inquiries to:

GCMA Office
Cystic Fibrosis Foundation
4550 Montgomery Ave.
Suite 1100 N
Bethesda, MD 20814

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CFF/NIH R01-Unfunded Award Policies and Guidelines Download (PDF)
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