Clinical Research Award

The Cystic Fibrosis Foundation offers competitive awards to support clinical research projects directly related to cystic fibrosis treatment and care.

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Clinical Research Awards are offered to provide support for investigator-initiated clinical research projects that have the potential to make an important contribution to the Cystic Fibrosis Foundation’s mission. Research projects may address diagnosis, treatment, management of disease or symptom, or the pathophysiology of cystic fibrosis using clinical (observational/interventional), translational, or epidemiologic study approaches. Applicants must demonstrate access to sufficient numbers of CF patients and appropriate controls. Applicants interested in the Multiple-PI option should contact the Program Officer, Dara Riva, at driva@cff.org.

Up to $150,000 per year (plus 12% indirect costs) for a maximum of three years may be requested for single-center clinical research awards.

For multi-center clinical research, the potential award is up to $350,000 per year (plus 12% for indirect costs) for a maximum of three years.

Up to an additional $50,000 over the entire project period may be available via supplemental funding.

Supplemental Funding to Address High Priority Areas  
  
Health Equity Supplement: Applicants may request an additional $50,000 (plus 12% indirect costs) over the entire project period to either advance our knowledge of health disparities in cystic fibrosis or enhance the diversity, equity, and inclusion in the biomedical workforce. 

Applicants must be independent investigators. Fellows may submit applications; however, funding will be considered only if they will hold a faculty-level appointment at the time of the award. Industry-sponsored research projects are not eligible for this award.

Areas of Encouragement

Areas of Encouragement are research topics that are considered gaps in our knowledge in the detection and monitoring, diagnosis, or treatment of a CF complication. The Areas of Encouragement will be updated on a biennial basis during Guidance, Action, Projection (GAP) Meetings and will be informed by GAP meeting attendees, community surveys, CF Foundation workshop recommendations, and other areas of focus identified by guidelines committees or Foundation/TDN research working groups.  The 2023 Areas of Encouragement can be found in the GAP Meeting executive summary. Learn more about the Foundation's Key Research Priorities.
 
Applicants to the funding opportunities reviewed by the Clinical Research Committee are highly encouraged, but not required, to submit research proposals that address one or more Areas of Encouragement. 

For specific questions regarding your proposal and the CF Foundation's research priorities, please contact the Program Officer, Dara Riva, at driva@cff.org.

Policies and Guidelines

Please review the Spring 2025 Policies and Guidelines for complete submission information.

Deadlines

All letters of intent and full applications for the Spring and Fall 2025 cycles must be submitted online at awards.cff.org by 5 p.m. ET.

Spring 2025

  • Letter of Intent: October 10, 2024
  • Full application: February 18, 2025

Fall 2025

  • Letter of Intent: April 3, 2025
  • Full application: August 14, 2025

For More Information

Those who are interested in any funding programs offered by the Foundation may get further information, or discuss the potential relevance of their studies or research by contacting Angela Minucci, the pre-award specialist for this program, at aminucci@cff.org

Grants and Contracts Management and Administration (GCMA) Office inquiries can be sent to:

GCMA Office
Cystic Fibrosis Foundation
4550 Montgomery Ave.
Suite 1100 N
Bethesda, MD 20814
800-FIGHT-CF
301-841-2614

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Role of Community Members in CF Clinical Research Download (PDF)
GAP Meeting Executive Summary Download (PDF)
Clinical Research Award Policies and Guidelines Download (PDF)
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