Clinical Research Award

The Cystic Fibrosis Foundation offers competitive awards to support clinical research projects directly related to cystic fibrosis treatment and care.

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Clinical Research Awards are offered to provide support for investigator-initiated clinical research projects that have the potential to make an important contribution to the Cystic Fibrosis Foundation’s mission. Research projects may address diagnosis, treatment, management of disease or symptom, or the pathophysiology of cystic fibrosis using clinical (observational/interventional), translational, or epidemiologic study approaches. Applicants must demonstrate access to sufficient numbers of CF patients and appropriate controls. Applicants interested in the Multiple-PI option should contact the Program Officer, Dara Riva, at

Up to $150,000 per year (plus 12% indirect costs) for a maximum of three years may be requested for single-center clinical research awards.

For multi-center clinical research, the potential award is up to $350,000 per year (plus 12% for indirect costs) for a maximum of three years.

Up to an additional $100,000 over the entire project period may be available via supplemental funding.

*NEW* Supplemental Funding to Address High Priority Areas  
Remote Collection Supplement:
Applicants may request an additional $50,000 (plus 12% indirect costs) over the entire project period to include an additional aim that leverages the proposed main research study aims that address important gaps in knowledge and improve our understanding of the utility of remote collection of either specimens, endpoints, and/or clinical data to address these gaps in knowledge. This supplement is not intended to support Quality Improvement research in sample collection or patient use of daily therapies.  
Health Equity Supplement: Applicants may request an additional $50,000 (plus 12% indirect costs) over the entire project period to either advance our knowledge of health disparities in cystic fibrosis or enhance the diversity, equity, and inclusion in the biomedical workforce. 

Applicants must be independent investigators. Fellows may submit applications; however, funding will be considered only if they will hold a faculty-level appointment at the time of the award. Industry-sponsored research projects are not eligible for this award.

Areas of Encouragement

Areas of Encouragement are research topics that are considered gaps in our knowledge in the detection and monitoring, diagnosis, or treatment of a CF complication. The Areas of Encouragement will be updated on a biennial basis during Guidance, Action, Projection (GAP) Meetings and will be informed by GAP meeting attendees, community surveys, CF Foundation workshop recommendations, and other areas of focus identified by guidelines committees or Foundation/TDN research working groups.  The 2023 Areas of Encouragement can be found with the Policies and Guidelines available in the download box on the right. To learn more about the research priorities of the CF Foundation, read the GAP Meeting executive summary.
Applicants to the funding opportunities reviewed by the Clinical Research Committee are highly encouraged, but not required, to submit research proposals that address one or more Areas of Encouragement. 

For specific questions regarding your proposal and the CF Foundation's research priorities, please contact the Program Officer, Dara Riva, at

Policies and Guidelines

Please review the Spring 2024 and Fall 2024 Policies and Guidelines for complete submission information.


All letters of intent and full applications for Spring 2024 and Fall 2024 must be submitted online at by 5 p.m. ET.

Spring 2024

  • Letter of Intent: September 21, 2023
  • Full application: February 13, 2024

Fall 2024

  • Letter of Intent: April 4, 2024
  • Full application: August 13, 2024

For More Information

Those who are interested in any funding programs offered by the Foundation may get further information, or discuss the potential relevance of their studies or research by contacting the Grants and Contracts Management and Administration Office (GCMA) at

Please Direct Inquiries to:

GCMA Office
Cystic Fibrosis Foundation
4550 Montgomery Ave.
Suite 1100 N
Bethesda, MD 20814

1 In 2017, the CF Foundation created the Lung Transplant Initiative to address the unmet needs of people living with cystic fibrosis with advanced lung disease. The mission of this initiative is to improve the care and long-term outcomes of individuals with CF and advanced lung disease. For more information about this initiative, or the CF Foundation’s priorities in lung transplant research, please email Abigail Thaxton at

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Researcher Resources
Clinical Research Award Policies and Guidelines Download (PDF)
Role of Community Members in CF Clinical Research Download (PDF)
GAP Meeting Executive Summary Download (PDF)
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