Clinical Research Awards are offered to provide support for investigator-initiated clinical research projects that have the potential to make an important contribution to the Cystic Fibrosis Foundation’s mission. Research projects may address diagnosis, treatment, management of disease or symptom, or the pathophysiology of cystic fibrosis using clinical (observational/interventional), translational, or epidemiologic study approaches. Applicants must demonstrate access to sufficient numbers of CF patients and appropriate controls. Applicants interested in the Multiple-PI option should contact the Program Officer, Dara Riva, at driva@cff.org.
Up to $150,000 per year (plus 12% indirect costs) for a maximum of three years may be requested for single-center clinical research awards.
For multi-center clinical research, the potential award is up to $350,000 per year (plus 12% for indirect costs) for a maximum of three years.
Up to an additional $50,000 over the entire project period may be available via supplemental funding.
Supplemental Funding to Address High Priority Area Health Equity Supplement:
NOTE: Funding for Health Experiences and Outcomes Supplements is based on availability of funds. If sufficient funds become available at the end of the calendar year, awardees will be notified to submit budget revisions to reflect the supplement. Do not include the Health Experiences and Outcomes Supplement request in your budget with your submissions.
Health Experiences and Outcomes Supplement: An additional $50,000 (plus 12% indirect costs) over the entire project period may be available to the applicant. Health Experiences and Outcomes supplements can be used for the following:
- Improve our understanding of health disparities in cystic fibrosis
- Enhance the range of perspectives and experience of the biomedical workforce
- Support the translation of validated PROMs, study materials (including informed consent documents), and/or the use of interpreters
Applicants must be independent investigators. Fellows may submit applications; however, funding will be considered only if they will hold a faculty-level appointment at the time of the award. Industry-sponsored research projects are not eligible for this award.
It is recommended that applicants speak with program staff prior to submission of a letter of intent to ensure the project design is in line with the goals of this RFA. For specific questions regarding your project and the CF Foundation's research priorities, please contact the Program Officer, Dara Riva, at driva@cff.org.
Policies and Guidelines
Please review the Fall 2026 Policies and Guidelines for complete submission information.
Deadlines
All letters of intent and full applications for the Spring and Fall cycles must be submitted online at awards.cff.org by 5 p.m. ET.
Fall 2026
- Letter of Intent: April 2, 2026
- Full application: August 17, 2026
For More Information
Those who are interested in any funding programs offered by the Foundation may get further information or discuss the potential relevance of their studies or research by contacting Angela Minucci, the pre-award manager for this program, at aminucci@cff.org.
Grants and Contracts Management and Administration (GCMA) Office inquiries can be sent to:
GCMA Office
Cystic Fibrosis Foundation
4550 Montgomery Ave.
Suite 1100 N
Bethesda, MD 20814
800-FIGHT-CF
301-841-2614
