mRNA therapy is one way to deliver the correct genetic instructions to cells, which would allow them to make functional CFTR protein regardless of an individual’s CF mutations.
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Cystic fibrosis is caused by mutations in both copies of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Scientists are examining whether it is possible to correct the mutations through a process called gene editing.
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Newborn screening (NBS) is a program run by each state to identify babies born with certain health conditions, including cystic fibrosis. Although a sweat test should ultimately be done to rule out or confirm a CF diagnosis, NBS can help you and your health care providers take immediate steps to keep your child as healthy as possible.
Dr. Dorothy Andersen first wrote about cystic fibrosis in 1938, and our understanding of the disease has significantly evolved since. There are still many misconceptions about what CF looks like today, from the person who lives with the disease to how it manifests.
At the Cystic Fibrosis Foundation, we commit to equity, racial justice, diversity, and inclusion as core principles guiding our efforts to provide all people with CF the opportunity to live long, fulfilling lives.
When you have cystic fibrosis, there are potential complications related to pregnancy. But as part of the planning process, you can learn more about these complications and how to partner with your CF care team to evaluate these risks based on your personal situation.
Women with CF have thicker cervical mucus and can have ovulation issues due to poor nutrition. However, the majority of women with CF are fertile and can become pregnant if appropriate contraception is not used.
The Cystic Fibrosis Foundation is aggressively pursuing potential treatments for people with CF who have nonsense and rare mutations who will not benefit from drugs known as modulators, which correct the malfunctioning cystic fibrosis transmembrane conductance regulator (
The Robert J. Beall Award, created in 2015, recognizes members of the CF scientific community whose work embodies and carries on Beall's innovative, determined and collaborative spirit in driving advances in CF research.