Although cystic fibrosis affects many parts of the body, the focus is often on the lungs because of the disease's effect on breathing.
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Autogenic drainage (AD) means “self-drainage” and uses different speeds of breathing to move mucus. To do it, your respiratory therapist can teach you how to control your breaths. You will learn how fast and deeply to breathe to fill certain parts of your lungs with air. AD can take some practice and is usually recommended for people age 8 and older.
Chest physical therapy (CPT or Chest PT) is an airway clearance technique (ACT) to drain the lungs, and may include percussion (clapping), vibration, deep breathing, and huffing or coughing.
Coughing is the most basic airway clearance technique (ACT). It can be an involuntary reflex or it can be controlled as a healthy, natural way for the lungs to get rid of mucus.
Positive expiratory pressure (PEP) therapy gets air into the lungs and behind the mucus using extra (collateral) airways.
Bronchodilators may widen airways by helping the surrounding muscles relax. This could allow more air to travel through the airways, which may help other medications work more effectively.
Cystic fibrosis biological samples are available to qualified researchers to help develop promising new studies that will support CF research and aid in drug development and drug discovery.
The goal of the CFTR Chemical Compound program is to enable cystic fibrosis research scientists to test known cystic fibrosis transmembrane conductance regulator (CFTR) modulating compounds in different functional assays.
Every person has two copies of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. A person must inherit two copies of the CFTR gene that contain mutations — one copy from each parent — to have cystic fibrosis.
In an international research project, scientists are examining cystic fibrosis transmembrane conductance regulator (CFTR) mutations to determine which ones cause CF and to provide additional information associated with these mutations. Their findings are available in an online searchable database.