Delivery of genetic therapies to affected tissues is a key challenge to developing new treatments for people with cystic fibrosis. In addition to investing in viral delivery and lipid nanoparticles, the Cystic Fibrosis Foundation is looking at the potential of a relatively new approach to delivery using an exceptionally small synthetic molecule called a polymer nanoparticle.
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The funding will help support research into the development of potential new modulator therapies for people with cystic fibrosis with an F508del mutation.
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Funding will support a Phase 2b trial of phage therapy for chronic Pseudomonas aeruginosa lung infections.
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