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About the CF Foundation | CFTR Modulators FDA Approves Ivacaftor for People with R117H Mutation of Cystic Fibrosis

The U.S. Food and Drug Administration (FDA) announced today that it has approved the use of ivacaftor (Kalydeco™) to treat people with cystic fibrosis ages 6 and older who have the R117H mutation.

| 2 min read
About the CF Foundation | CFTR Modulators Cystic Fibrosis Foundation Therapeutics Announces $15 Million Research Project for Development of Novel CF Treatment

Cystic Fibrosis Foundation Therapeutics Inc., the nonprofit affiliate of the Cystic Fibrosis Foundation, announced today a $15 million research agreement with biopharmaceutical company Shire plc to support the development of a new cystic fibrosis treatment targeting the underlying cause of the disease.

| 2 min read
About the CF Foundation | CFTR Modulators | Clinical Trials Letter to the Community on Exciting Vertex Clinical Trials Results

This morning, Vertex Pharmaceuticals announced the results from the Phase 3 clinical trials of ivacaftor (Kalydeco™) and lumacaftor (VX-809) in people with two copies of the F508del mutation.

| 4 min read