Pilot and Feasibility Awards

Pilot and feasibility awards are intended to support basic science research studies focused on developing and testing new hypotheses in areas relevant to cystic fibrosis.

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These awards are for developing and testing new hypotheses and/or methods, and supporting promising new investigators as they establish themselves in research areas relevant to cystic fibrosis. Information derived from such studies will hopefully lead to submission to other funding agencies, such as the National Institutes of Health.

Proposed work must be hypothesis-driven and must reflect innovative approaches to critical questions in CF research.

Support may be requested for $50,000 per year (plus 12% for indirect costs) for up to two years.

Priority will be placed on those projects that propose to better understand the mechanisms behind disease pathophysiology and to develop strategies to prevent or treat CF. Projects proposing interventional clinical studies must not be submitted through this funding mechanism and should instead apply for a Clinical Pilot and Feasibility Award.

Applicants seeking to submit proposals focused on topics such as the restoration of CFTR protein function or approaches to fix/replace the defective CFTR gene should apply through the Path to a Cure (PTAC) Pilot and Feasibility Award Program. Topics for the PTAC program include, but are not limited to, characterization of rare CFTR mutations, nonsense modulation, gene editing/replacement strategies, and characterizing cellular targets for CFTR correction. 

Policies and Guidelines

Applicants may submit only one Pilot and Feasibility Award application in 2024 (either the Spring or Fall cycle).

Please review the 2024 Spring Policies and Guidelines for complete submission information.


Spring cycle applications: May 2, 2024

Applications must be submitted online at awards.cff.org by 5 p.m. ET.

For More Information

Those who are interested in any funding programs offered by the Cystic Fibrosis Foundation may get further information, or discuss the potential relevance of their studies or research by contacting the Grants and Contracts Management and Administration (GCMA) office at grants@cff.org.

Please Direct Inquiries to:

GCMA Office
Cystic Fibrosis Foundation
4550 Montgomery Ave.
Suite 1100 N 
Bethesda, MD 20814

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