PTC Therapeutics has discontinued development of ataluren as a potential treatment for people with cystic fibrosis caused by a nonsense mutation. The Cystic Fibrosis Foundation is supporting efforts to pursue treatments for people with CF who have a nonsense, splicing or other rare mutations.
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The studies aim to improve early detection of chronic lung allograft dysfunction (CLAD), the leading cause of lung transplant failures.
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Many people with cystic fibrosis face the possibility of a lung transplant. Lung transplantation can extend and improve your quality of life, but it involves an extensive evaluation process and a commitment to living the lifestyle required to keep your new lungs healthy.