Therapeutics Development Network

Therapeutics Development Network

The Cystic Fibrosis Therapeutics Development Network is the largest CF clinical trials network in the world. We bring together experts from across the country to evaluate the safety and effectiveness of new CF therapies through clinical studies.

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Introduction to the Therapeutics Development Network

Through efficient study design, optimized clinical trial execution, and high-quality data, the Therapeutics Development Network (TDN) helps speed the delivery of new and better therapies to people with cystic fibrosis.

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Why Work With the TDN

Therapeutics Development Network investigators and research staff work every day to promote quality, safety, and efficiency in cystic fibrosis clinical research and help speed the delivery of new and better therapies to people with CF.

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TDN Sponsor Engagement

Effective clinical development plans and good study design can save sponsors and investigators time and money, leading to faster development of potential new therapies for people with cystic fibrosis.

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TDN Protocol Review Process

The Therapeutics Development Network's (TDN) Protocol Review Process ensures optimum safety and quality in cystic fibrosis clinical trial protocols.

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Clinical Research Executive Committee

The Clinical Research Executive Committee (CREC) assesses how a specific protocol fits within the overall clinical research priorities of the cystic fibrosis community and assigns it a rating.

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Therapeutics Development Centers

The Therapeutics Development Network includes 90 clinical research centers, called Therapeutics Development Centers.

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Data Safety Monitoring Board

The primary responsibility of the independent Data Safety Monitoring Board is to protect the safety and welfare of people who participate in clinical trials approved by the Therapeutics Development Network.

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TDN Women's Health Research Working Group

To address the unique and emerging needs of women with cystic fibrosis, the Cystic Fibrosis Foundation has established a research working group to identify knowledge gaps, determine research priorities, and develop the infrastructure needed to conduct the research.

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Study and Site Management

The strength of the Therapeutics Development Network Coordinating Center lies in our unparalleled experience in setting up and managing cystic fibrosis studies and our intimate knowledge of the CF research community.

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Biostatistics and Clinical Data Management

The Therapeutics Development Network Coordinating Center Biostatistics and Clinical Data Management team has extensive expertise in the support of both controlled clinical trials and observational studies. We offer full statistical and data management support -- from planning to implementation to reporting.

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Medical/Safety Monitoring

The Therapeutics Development Network Coordinating Center can provide coverage and coordination for the review and reporting of serious adverse events that may occur during the course of cystic fibrosis clinical studies.

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Research Pharmacy Services

The Therapeutics Development Network Coordinating Center partners with the Investigational Drug Service at Seattle Children's Hospital to provide pharmacy-related support for multi-center CF clinical studies.

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