As of May 2021, no applications will be accepted through the proposalCENTRAL portal. All CF Foundation-supported awards can be found in our new grants management system at awards.cff.org.
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Independent Research Funding Opportunities
| Success With Therapies Research Consortium Award |
Purpose: To provide the opportunity for clinically trained physicians to identify and study interventions to enhance successful self-management and related health outcomes among individuals with CF. Funding: Up to $21,000 in direct costs plus 12% of indirect costs ($23,520 total costs) per year Duration: Up to three years Deadline: March |
| Patient Registry Research: Application of Advanced Methods |
Purpose: To use innovative registry-based analyses that aim to test novel methods to advance the use of the Foundation's Patient Registry. Funding: Up to $150,000 per year for up to two years, plus an additional 12% indirect costs. Duration: Two years Deadlines: Letter of Intent: August 9, 2023; full application: November 14, 2023 |
| Multiple Principal Investigator Award |
Purpose: To provide support for multi-investigator-initiated clinical research projects that have the potential to make an important contribution to the Cystic Fibrosis Foundation’s mission. Funding: Each applicant may request up to $200,000 per year for up to three years + an additional 12% indirect costs per year; lead institution may request up to $25,000 in additional direct costs per year Duration: 3 years Deadlines: LOI April, full application August |
| Gastrointestinal Manifestations of CF: Basic Science Projects |
Purpose: To solicit and fund projects that will improve our understanding of the biological basis for the development and progression of gastrointestinal manifestations in cystic fibrosis as well as to identify potential novel therapeutic strategies to manage and treat them Funding: Up to $150,000 per year + up to 12% indirect costs Duration: 3 years Deadline: December |
| Path to a Cure Collaborative Research Grant |
Purpose: To facilitate research that will contribute to the development of new therapies or therapeutic strategies to treat cystic fibrosis with an emphasis on advancing CFTR gene repair and replacement approaches. Funding: May not exceed $1 million/year + 12% indirect costs Duration: 3 years Deadline: July |
| Pilot and Feasibility Award |
Purpose: To support (non-Path to a Cure related) basic science research studies focused on developing and testing new hypotheses in areas relevant to cystic fibrosis. Funding: $50,000/year + 12% indirect costs Duration: 2 years Deadlines: May & December |
| Path to a Cure Pilot and Feasibility Award |
Purpose: To support basic science research studies focused on developing and testing new hypotheses in areas relevant to the Path to a Cure Initiative (see guidelines for areas of interest). Funding: $50,000/year + 12% indirect costs Duration: 2 years Deadlines: May & December |
| Path to a Cure Pioneer Award |
Purpose: To support paradigm-shifting technologies that have the potential to cure CF at the cellular and/or genetic level Funding: As agreed upon + 12% indirect costs Duration: 3 years Deadline: Rolling |
| Clinical Pilot and Feasibility Award |
Purpose: To enable investigators to collect sufficient preliminary data to determine the best strategies and methods for approaching a major question that ultimately will require assessment through a larger scale research and/or multi-center, collaborative clinical trial. Funding: $80,000-$150,000/year + 12% indirect costs Duration: 2 years Deadlines:
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| Research Grants |
Purpose: To support (non-Path to a Cure related) basic science research that will provide new insights that contribute to the understanding of the basic etiology and pathogenesis of cystic fibrosis. Funding: $150,000/year + 12% indirect costs Duration: 3 years Deadlines: May & December |
| Path to a Cure Research Grants |
Purpose: To support basic science research that may enable the development of new therapies that directly impact CFTR function (see guidelines for areas of interest). Funding: $150,000/year + 12% indirect costs Duration: 3 years Deadlines: May & December |
| Clinical Research Award |
Purpose: To provide support for investigator-initiated clinical research projects that have the potential to make an important contribution to the Cystic Fibrosis Foundation's mission. Research projects may address diagnosis, treatment, management of disease or symptom, or the pathophysiology of cystic fibrosis, using clinical, (observational/interventional), translational, or epidemiologic study approaches. Funding: $150,000 - $350,000 + 12% indirect costs Duration: 3 years Deadlines:
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| CFF/NIH R01 Unfunded Award |
Purpose: To provide bridge funding for CF-relevant R01 (or equivalent) applications that were submitted to NIH (or other governmental agencies) that scored in the 40th percentile but were not awarded by the funding agency. Funding: $125,000/year (indirect costs not allowed) Duration: Up to 2 years or until NIH funding is secured Deadline: Rolling |
Training, Career Development, and Mentored Research Funding Opportunities
| Medical Resident Research Award |
Purpose: To introduce residents to research through participation in a CF-relevant research project with the goal to develop and maintain interest in a career in CF research or as a CF care provider. Funding: $10,000 for one year Duration: 1 year Deadline: November |
| Student Traineeship Award |
Purpose: To introduce students to cystic fibrosis research and encourage them to remain engaged in the field. Funding: $4,000 (indirect costs not allowed) Duration: 10-weeks to 1 year Deadline: Rolling |
| Travel Award Supplement |
Purpose: To support PhD students, postdocs, and junior faculty to participate in off-site training to learn new research skills and techniques to advance their research. Funding: $3,000 (indirect costs not allowed) Duration: Variable Deadline: Rolling |
| Student Loan Repayment Program (Only for awardees with active Clinical Fellowships, LeRoy Matthews Awards, Harry Shwachman Awards, DIGEST awards, and EnVision awards) |
Purpose: To offer eligible awardees assistance with student loan payments for educational loans acquired in the pursuit of a graduate-level degree. Funding: Up to $14,000 + 25% offset Duration: One-time payment/eligible year Deadline: Rolling |
Postdoctoral Fellows (Ph.D., D.V.M., Pharm.D., or equivalent terminal degree)
| Clinical Postdoctoral Research Fellowship Award |
Purpose: To enable training in new research areas and methods to advance the scientific knowledge of the applicant and to collect data to enable their transition into an impactful research career. Funding: Up to $75,000 in the first year and up to $76,500 in the second year (indirect costs not allowed) Duration: 2 years Deadline: November |
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| Postdoctoral Research Fellowship Award |
Purpose: To support (non-Path to a Cure related) postdoctoral research training related to cystic fibrosis. Funding: Up to $75,000 in the first year and $76,000 in the second year (indirect costs not allowed) Duration: 2 years Deadlines: May & December |
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| Path to a Cure Postdoctoral Research Fellowship Award |
Purpose: To support postdoctoral research training in topics related to the CFF Path to a Cure Initiative (see guidelines for areas of interest). Funding: Up to $75,000 first year and $76,000 second year (indirect costs not allowed) Duration: 2 years Deadlines: May & December |
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| Postdoc-to-Faculty Transition Awards |
Purpose: To support postdoctoral research fellows pursuing non-Path-to-Cure-related research during their fellowship and aid in their transition to an independent research faculty position. Funding: Up to $86,000 per year during the training phase of the award. The faculty phase includes $80,000 for salary support and $30,000 for research support. (Indirect costs not allowed.) Duration: 3 – 5 years Deadline: December |
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| Path to a Cure Postdoc-to-Faculty Transition Award |
Purpose: To support postdoctoral research fellows during their CF fellowship and aid in their transition to an independent research faculty position. Funding: Up to $75,000 in the first year, and up to $76,000 in the second year. Indirect costs are not allowable. Refer to the Policies and Guidelines for funding support table. Duration: Up to 5 years of combined support for research training and the initiation of independent research career. Deadline: December |
Clinical Fellows (M.D., D.O., or equivalent clinical degree)
| Clinical Fellowship Program Award |
Purpose: The intent of this program is to support fellowship programs that integrate CF care and mentorship early in their fellowship curriculum. Funding: $78,000, which includes up to $72,000 for salary and benefits and $2,000 each for travel and/or registration fees for three fellows to attend NACFC Duration: One year Deadline: September 2024 |
| Clinical Fellowship Awards — Education and Training |
Purpose: To encourage specialized training in the early career development stage, provide exposure to CF research and patient care, and prepare well-qualified candidates for careers related to CF Funding: $73,000 for salary and benefits and $2,000 to attend NACFC per year (indirect costs not allowed) Duration: 1-2 years Deadline: February |
| Clinical Fellowship Awards — Research |
Purpose: For physicians who are engaged in fellowship training in a subspecialty related to CF care and seek support for fellowship training and a well-defined, CF-relevant research project. Funding: $105,000 in direct costs per year (indirect costs not allowed) Duration: 1-2 years Deadline: February |
| LeRoy Matthews Physician-Scientist Award |
Purpose: To encourage outstanding newly trained internists and pediatricians to enhance clinical proficiency in CF-related subspecialties and to develop the necessary research capabilities to become independent biomedical investigators. Funding: Ranges from $73,000 stipend plus $12,000 research and development for first year to $100,000 stipend plus $33,000 research and development for sixth year (indirect costs not allowed) Duration: 3-6 years Deadline: February |
Junior Faculty Independent Investigator
| Research Additional Mentoring Program (RAMP) Award |
Purpose: To enable promising early-career physician scientists seeking additional research mentoring outside of their home academic institutions to enhance their clinical or translational research proficiency and support their development of the necessary clinical research capabilities to become independent investigators. Funding: Up to $42,420 per year Duration: 3 years Deadline: May |
| Harry Shwachman Clinical Investigator Award |
Purpose: To provide the opportunity for promising, clinically trained physicians with a commitment to research to develop into independent biomedical researchers who have active involvement in CF-related areas. Funding: $100,000 salary support per year plus $33,000 for supplies (indirect costs not allowed) Duration: 3 years Deadline: February |
| CFF/NIH K-Unfunded Award |
Purpose: To support excellent CF-focused researchers whose projects have been submitted to and approved by the NIH but cannot be supported by available funds. Funding: $80,000 per year (indirect costs not allowed) Duration: Up to 2 years or until NIH funding is secured Deadline: Rolling |
| CFF/NIH K-Boost Award |
Purpose: To provide supplemental funding to qualified and promising scientists early in their faculty careers who have obtained K funding from the National Institutes of Health in areas that reflect the Cystic Fibrosis Foundation's research priorities. Funding: $50,000 (indirect costs not allowed) Duration: Up to 5 years/duration of the NIH K-award Deadline: Rolling |
| Clinical Research Scholars Program Award (CRSP w/LOI) |
Purpose: To enable outstanding early career pediatricians and internists to enhance their clinical research proficiency and to develop the necessary clinical research capabilities to become independent investigators who formulate and lead multi-center, clinical research studies. Funding: Up to $45,140 per year (plus travel) Duration: 3 years Deadlines: LOI March, full application June |
Care Enhancement and Care Team Development Funding Opportunities
| CF Statistical Expertise and Network (CF StatNet) Award |
Purpose: This award will promote greater collaborative integration of statisticians and CF clinical investigators at TDN institutions by funding local statisticians and integrating them into the CF Statistical Research Network (CF StatNet). Funding: Year 1, 35% FTE; Year 2, 25% FTE; Year 3, 20% FTE Duration: Three years Deadline: LOI August 2024, full application December 2024 |
| Clinical Trials in Organ Transplantation Ancillary Studies (w/LOI) |
Purpose: For research projects that aim to use available clinical trials in organ transplantation specimens and/or clinical data to improve knowledge of chronic lung allograft dysfunction (CLAD) pathogenesis and explore new approaches to detection, prevention, monitoring, or treatment of CLAD. Funding: Between $50,000 to $100,000 per year for up to two years plus 12% indirect costs Duration: 2 years Deadlines: LOI: June 13, 2024; Full application: September 12, 2024 |
| Chronic Lung Allograft Dysfunction Biomarkers RFA |
Purpose: For research projects that aim to identify biomarkers, improve knowledge of pathogenesis, and explore new approaches to treatment of chronic lung allograft dysfunction (CLAD). Funding: Up to $150,000 per year for up to two years, plus an additional 12% indirect costs for independent research; and up to $350,000 per year for up to two years, plus 12% indirect costs for collaborative research. Duration: 2 years Deadlines: LOI: May 21, 2024; Full application: August 15, 2024 |
| LEAPP CF: Leadership and Education Advanced Practice Provider Fellowship Program |
Purpose: To expand the number of CF providers in outpatient pediatric and adult care programs Funding: Up to $74,110 in Year 1; up to $77,200 in Year 2, plus 12% indirect costs Duration: 2 years Deadline: March 7, 2023 |
| National Resource Center Award |
Purpose: The intent of this program is to support National Resource Centers that will address and advance biomarkers and clinical outcome measures relevant to evolving needs over the next five years. Funding: $175,000 per year for up to five years, plus 12% indirect costs. Duration: 5 years Deadline: November 2024 |
| Program for Adult Care Excellence (PACE) Award |
Purpose: To meet the growing demand for physicians trained to address the unique medical needs of adult patients with CF and a need for greater participation from adult care programs in the clinical research enterprise Funding: $38,435 (per year) Duration: 3 years Deadline: October |
| Developing Innovative Gastroenterology Specialty Training (DIGEST) Program |
Purpose: To expand the availability of CF-GI experts trained to address the unique gastroenterologic needs of CF patients and the need for a greater GI focus in the clinical research enterprise Funding: $30,000 (first year) Duration: 3 years Deadline: May |
| EnVision CF: Emerging Leaders in CF Endocrinology III Program |
Purpose: To fund the training of physicians interested in developing expertise in the endocrinologic care of patients with CF Funding: Up to $54,000 per year Duration: 3 years Deadline: February 15, 2023 |
| Implementation of Outpatient Clinical Pharmacy Services: Award for a Pharmacist and Pharmacy Technician |
Purpose: To facilitate development and implementation of outpatient clinical pharmacy services at accredited CF care centers Funding: Up to $190,000 spread over three years (plus 12% indirect costs) Duration: 3 years Deadline: January 30, 2025 |
| Implementation of Outpatient Physical Therapy Services |
Purpose: To facilitate development and implementation of outpatient physical therapy services at accredited CF care centers Funding: Up to $90,000 spread over three years (plus 12% indirect costs) Duration: 3 years Deadline: April |
| Screening Improvement Program (SIP) for Optimizing Diagnosis of Infants |
Purpose: Quality improvement (QI) awards for projects designed to improve the early diagnosis of CF through the newborn screening system and/or to improve the initial management of infants with positive screening tests and the follow-up communications with their families. Funding: $75,000 per year for 2 years (plus 12% indirect costs) Duration: 2 years Deadline: July |
| Tools for Remote CF Care Delivery: Application of QI Science |
Purpose: Awards for innovative, multi-site quality improvement (QI) projects that aim to test tools and processes facilitating remote CF care delivery. Funding: Up to $250,000 per year (plus 12% indirect costs) Duration: 2 years Deadlines: LOI: March; Full application: June |